Study offers clue to spreading TB
Study offers clue to spreading TB
2008-04-01Newsfeed
A significant breakthrough has been made in research into how tuberculosis spreads between patients, scientists have claimed.
A significant breakthrough has been made in research into how tuberculosis spreads between patients, scientists have claimed.TB bacteria accumulate "fat" that may help them survive while passing from one person to another and also boost their resistance to drugs, a team of microbiologists from the University of Leicester and University of London found.The established view that TB bacteria coughed up by infected individuals multiply rapidly as the disease spreads could be challenged by the findings.The have discovered that the number of bacteria may not grow. Instead, the bacteria survive in large numbers by gathering fatty deposits and effectively "shutting down" to journey from one person to another.Lead investigator Professor Mike Barer, from the University of Leicester, said: "Strenuous efforts are being made to reduce the global burden of tuberculosis, a disease which kills four people every minute."Our success so far has been limited for many reasons; one of these is our failure to control the spread of TB from one person to another. Very little is known about this vital part of the bacterium's life cycle."If scientists could understand more about the transmission of TB between people, they might identify new therapeutic and preventative targets."Copyright © The Press Association 2008
